Chwastek J, Kędziora M, Borczyk M, Korostyński M, Starowicz K. Mimicking the Human Articular Joint with In Vitro Model of Neurons-Synoviocytes Co-Culture. Int J Stem Cells. 2023 Nov 24. doi: 10.15283/ijsc23043. Epub ahead of print. PMID: 37996245;

Malek N, Mlost J, Kostrzewa M, Rajca J, Starowicz K. Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis. Mol Neurobiol. 2023 Sep 21. doi: 10.1007/s12035-023-03619-x. Epub ahead of print. PMID: 37731080;

Kędziora M, Boccella S, Marabese I, Mlost J, Infantino R, Maione S, Starowicz K. Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB1 receptor following osteoarthritis. Neuropharmacology. 2023 Jan 1;222:109304. doi: 10.1016/j.neuropharm.2022.109304. Epub 2022 Oct 28. PMID: 36341807;

Honkisz-Orzechowska E, Popiołek-Barczyk K, Linart Z, Filipek-Gorzała J, Rudnicka A, Siwek A, Werner T, Stark H, Chwastek J, Starowicz K, Kieć-Kononowicz K, Łażewska D. Anti-inflammatory effects of new human histamine H3 receptor ligands with flavonoid structure on BV-2 neuroinflammation. Inflamm Res. 2022 Nov 12. doi: 10.1007/s00011-022-01658-z. Epub ahead of print. PMID: 36370200;

Malek N, Borowczyk J, Kostrzewa M, Pawlowska A, Drukala J, Starowicz K. The Impact of JWH-133 on Articular Cartilage Regeneration in Osteoarthritis Via Metalloproteinase 13-Dependent Mechanism. Cannabis Cannabinoid Res. 2022 Nov 1. doi: 10.1089/can.2022.0107. Epub ahead of print. PMID: 36318796;

Chwastek J, Kędziora M, Borczyk M, Korostyński M, Starowicz K. Inflammation‐Driven Secretion Potential Is Upregulated in Osteoarthritic Fibroblast‐Like Synoviocytes. Int. J. Mol. Sci. 2022, 23, 11817. doi: 10.3390/ijms231911817;

Bryk M, Karnas E, Mlost J, Zuba‐Surma E, Starowicz K. MESENCHYMAL STEM CELLS AND EXTRACELLULAR VESICLES FOR THE TREATMENT OF PAIN: CURRENT STATUS AND PERSPECTIVES; Br J Pharmacol. 2022 Sep;179(17):4281-4299. doi: 10.1111/bph.15569.

Mlost J, Kac P, Kędziora M, Starowicz K. Antinociceptive and chondroprotective effects of prolonged β-caryophyllene treatment in the animal model of osteoarthritis: Focus on tolerance development. Neuropharmacology. 2022 Feb 15;204:108908. doi: 10.1016/j.neuropharm.2021.108908. Epub 2021 Nov 29.PMID: 34856202;

Mlost J, Kędziora M, Starowicz K. Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels. Pharmaceuticals (Basel). 2021 Sep 24;14(10):964. doi: 10.3390/ph14100964.PMID: 34681188;

Bryk M, Starowicz K. Cannabinoid-based therapy as a future for joint degeneration. Focus on the role of CB2 receptor in the arthritis progression and pain: an updated review. Pharmacological Reports, 2021; 1-19; doi: 10.1007/s43440-021-00270-y;

Bryk M, Chwastek J, Mlost J, Kostrzewa M, Starowicz, K. Sodium Monoiodoacetate Dose-Dependent Changes in Matrix Metalloproteinases and Inflammatory Components as Prognostic Factors for the Progression of Osteoarthritis.
Front Pharmacol . 2021 Apr 28;12:643605. doi: 10.3389/fphar.2021.643605.

Mlost J, Kostrzewa M, Borczyk M, Bryk M, Chwastek J, Korostyński M,  Starowicz K. CB2 agonism controls pain and subchondral bone degeneration induced by mono-iodoacetate: implications GPCR functional bias and tolerance development. Biomed Pharmacother. 2021 Apr;136:111283. doi: 10.1016/j.biopha.2021.111283a

Mugnaini C, Kostrzewa M, Bryk M, Mahmoud A M, Brizzi A, Lamponi S, … & Corelli F. Design, synthesis, and physicochemical and pharmacological profiling of 7-hydroxy-5-oxopyrazolo [4, 3-b] pyridine-6-carboxamide derivatives with antiosteoarthritic activity In Vivo.  J Med Chem . 2020 Jul 9;63(13):7369-7391. doi: 10.1021/acs.jmedchem.0c00595.

Mlost J, Bryk M, Starowicz K. Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action.  Int J Mol Sci . 2020 Nov 23;21(22):8870. doi: 10.3390/ijms21228870.

Mlost J, Wąsik A, Starowicz K. Role of endocannabinoid system in dopamine signalling within the reward circuits affected by chronic pain. Pharmacol Res. 2019 May;143:40-47. doi: 10.1016/j.phrs.2019.02.029. Epub 2019 Mar 1. Review.

Malek N, Starowicz K. Joint problems arising from lack of repair mechanisms: can cannabinoids help? Br J Pharmacol. 2019 May;176(10):1412-1420. doi: 10.1111/bph.14204. Epub 2018 Apr 22. Review.

Mlost J, Wąsik A, Michaluk JT, Antkiewicz-Michaluk L, Starowicz K. Changes in Monoaminergic Neurotransmission in an Animal Model of Osteoarthritis: The Role of Endocannabinoid Signaling. Front Mol Neurosci. 2018 Dec 20;11:466. doi: 10.3389/fnmol.2018.00466.

Mlost J, Kostrzewa M, Malek N, Starowicz K. Molecular Understanding of the Activation of CB1 and Blockade of TRPV1 Receptors: Implications for Novel Treatment Strategies in Osteoarthritis. Int J Mol Sci. 2018 Jan 24;19(2). pii: E342.

Korostynski M, Malek N, Piechota M, Starowicz K. Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat model. Funct Integr Genomics. 2018 Jan;18(1):79-87.

Pajak A, Kostrzewa M, Malek N, Korostynski M, Starowicz K. Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis. J Pain Res. 2017 Aug 21;10:1973-1989

Starowicz K, Finn DP.  Cannabinoids and Pain: Sites and Mechanisms of Action. Adv Pharmacol. 2017;80:437-475

Korostyński M, Małek N, Piechota M, Starowicz K. Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis. Int J Genomics. 2017;2017:1746426

Luongo L, Starowicz K, Maione S, Di Marzo V. Allodynia Lowering Induced by Cannabinoids and Endocannabinoids (ALICE). Pharmacol Res. 2017, 119:272-27722 

Malek N, Starowicz K.  Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems-A Novel Treatment Option for Chronic Pain Management. Front Pharmacol. 2016; 7:257

Malek N, Kostrzewa M, Makuch W, Pajak A, Kucharczyk M, Piscitelli F, Przewlocka B, Di Marzo V, Starowicz K.  The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. Pharmacol Res. 2016; 111:251-63.

Malek N, Popiolek-Barczyk K, Mika J, Przewlocka B, Starowicz K.  Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. Neural Plast. 2015;2015:130639.

Malek N, Mrugala M, Makuch W, Kolosowska N, Przewlocka B, Binkowski M, Czaja M, Morera E, Di Marzo V, Starowicz K. A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis. Pain. 2015 May;156(5):890-903.

Luongo L, Malcangio M, Salvemini D, Starowicz K. Chronic pain: new insights in molecular and cellular mechanisms. Biomed Res Int. 2015;2015:676725.

Malek N, Pajak A, Kolosowska N, Kucharczyk M, Starowicz K. The importance of TRPV1-sensitisation factors for the development of neuropathic pain. Mol Cell Neurosci. 2015 Mar;65:1-10.

Malek N, Kucharczyk M, Starowicz K. Alterations in the Anandamide Metabolism in the Development of Neuropathic Pain. Biomed Res Int. 2014;2014:686908.

Starowicz K, Di Marzo V. Non-psychotropic analgesic drugs from the endocannabinoid system:  “magic bullet” or “multiple-target” strategies?” Eur J Pharmacol. 2013 Sep 15;716(1-3):41-53.

Starowicz K, Makuch W, Korostynski M, Malek N, Slezak M, Zychowska M, Petrosino S, De Petrocellis L, Cristino L, Przewlocka B Di Marzo V. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism., PLoS One. 2013;8(4):e60040.

Starowicz K, Makuch W, Osikowicz M, Piscitelli F, Petrosino S, Di Marzo V, Przewlocka B. Spinal anandamide produces analgesia in neuropathic rats: possible CB(1)- and TRPV1-mediated mechanisms. Neuropharmacology. 2012 Mar;62(4):1746-55.

De Petrocellis L, SchianoMoriello A, Imperatore R, Cristino L, Starowicz K, Di Marzo V. A re-evaluation of 9-HODE activity at TRPV1 channels in comparison to anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. Br J Pharmacol. 2012 Dec;167(8):1643-51.

Starowicz K, Przewlocka B. Modulation of neuropathic-pain-related behavior by the spinal endocannabinoid/endovanilloid system. Phil. Trans. R. Soc. B. 2012 367, 3286-3299.